By establishing a biochemistry and biology laboratory, we at Cannerald AG invest in the future of cannabis. The laboratory infrastructure allows independent quality control of our cannabis products within the legal requirements. This ensures a consistently high quality of the products. The perfectly equipped laboratories allow basic research in the field of cultivation as well as research in the pharmaceutical field to be carried out at the highest level. This enables the optimization of the cultivation processes and the development of medicinal cannabis in a targeted manner.
Our biochemistry laboratory
In the biochemistry laboratory, organic plant materials are broken down, isolated, and analyzed. Mills (dispersers), microwave reactors, thermal shakers, and "liquid handling systems" of the latest generation enable semi-automated sample preparation. This results in a high output of the samples to undergo further analysis, as well as a reduction in error sources. For analytical separation and identification of secondary metabolites, a liquid chromatography system - coupled to a mass spectrometer (UPLC-MS/MS) and a gas chromatography system with the same detector (GC-MS/MS) - are in place. An inductively coupled plasma mass spectrometer (ICP-MS) is used to detect various elements in the ppb range. In addition, an automatized high-performance liquid chromatography system has been installed to preparatively isolate metabolites for research purposes.
Our biology laboratory
In the biology laboratory, microbiological detection is performed for quality control along with in vitro experiments to determine therapeutic effects. A safety cabinet for aseptic work, equipment for the traditional cultivation of bacteria, and a quantitative polymerase chain reaction (qPCR) are available for microbiological detection. Microscopes of the latest technology and a microplate absorption reader with high sensitivity are applied to investigate the therapeutic activities of metabolites. In this way, the infrastructure enables the analysis of cannabis at the level of DNA, RNA, metabolites - as well as indirectly proteins.